(spx® — 01)
PGX REPORTING SYSTEM
Pharmacogenomic AI
Pharmacogenomic AI
Pharmacogenomic AI
Pharmacogenomic AI
Pharmacogenomic AI
for modern labs.
for modern labs.
for modern labs
SignalPGx organizes genotype data, medication history, and clinical evidence into physician-ready PGx reports, powered by our state-of-the-art Medication Intelligence Simulation for drug response, risk stratification, dosing insights, and personalized prescribing medication support.
SignalPGx organizes genotype data, medication history, and clinical evidence into physician-ready PGx reports,
powered by our state-of-the-art Medication Intelligence Simulation for drug response, risk stratification, dosing insights, and personalized prescribing medication support.
SignalPGx organizes genotype data, medication history, and clinical evidence into physician-ready PGx reports, powered by our state-of-the-art Medication Intelligence Simulation for drug response, risk stratification, dosing insights, and personalized prescribing medication support.
SignalPGx organizes genotype data, medication history, and clinical evidence into physician-ready PGx reports,
powered by our state-of-the-art Medication Intelligence Simulation for drug response, risk stratification, dosing insights, and personalized prescribing medication support.
Pharmacogenomic intelligence
Evidence-backed reports
Precision prescribing support
Genotype to guidance
Medication response insights
Clinical decision support




PGx & lab experts
HIPAA & GDPR
compliant & secure




PGx & lab experts
HIPAA & GDPR
compliant & secure
Scan to book a call
with a PGx specialist
Scan to book a call
with a PGx specialist
(spx® — 02)
HOW WE THINK ABOUT PGX


Most PGx reporting systems are just static pdf and too complex. We designed a system with state of the art reporting from over 20+ sources globally and first of its kind Medication intelligence simulation.
Most PGx reporting systems are just static pdf and too complex. We designed a system with state of the art reporting from over 20+ sources globally and first of its kind Medication intelligence simulation.
Most PGx reporting systems are just static pdf and too complex. We designed a system with state of the art reporting from over 20+ sources globally and first of its kind Medication intelligence simulation.
Most PGx reporting systems are just static pdf and too complex. We designed a system with state of the art reporting from over 20+ sources globally and first of its kind Medication intelligence simulation.
Most PGx reporting systems are just static pdf and too complex. We designed a system with state of the art reporting from over 20+ sources globally and first of its kind Medication intelligence simulation.
We don’t start with models. We start with how decisions are made,
where processes fail, and how systems behave under pressure.
We don’t start with models. We start with how
decisions are made, where processes fail, and how
systems behave under pressure.
Tarek Younis
Principal AI Architect

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/4
(WDX® — 03)
OUR SERVICES
PGx Reporting Services
Four core capabilities designed to help labs launch, scale, and deliver physician-ready pharmacogenomic reports.
001.
PHARMACOGENOMIC INTELLIGENCE LAYER
From Genotype to Evidence-Graded PGx Reports
SignalPGx turns VCF, Agena MassARRAY plates, flexible instrument CSVs, and custom lab files into branded, evidence-graded PGx reports with SignalAI interpretation, medication intelligence, and medical-director review built in.


WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports
002.
50 pharmacogenes and ~950 guided medications
003.
15+ evidence sources fused into one intelligence graph
004.
Medical-director review, release and audit trail
002.
MEDICATION INTELLIGENCE SIMULATION
Test Medication Risk Before It Reaches the Patient
SignalPGx uses SignalAI and the Medication Intelligence Graph to model add, remove, or swap scenarios, recompute phenoconversion, detect drug-drug-gene interactions, and surface genotype-aware safer alternatives.


WHAT SIGNALPGx GENERATES
001.
Add / remove / swap medication scenarios
002.
Phenoconversion and drug-drug-gene interactions
003.
Genotype-aware dosing and safer alternatives
004.
SignalAI cited review with evidence refusal guardrails
003.
WHITE-LABEL LAB INFRASTRUCTURE
Launch Branded PGx Reporting in 5–7 Days
SignalPGx gives labs the reporting engine, file intake layer, SignalAI review workflow, branded report suite, and provider delivery infrastructure needed to launch PGx under their own brand without months of software buildout.


WHAT SIGNALPGx GENERATES
001.
Multi-format PGx engine: VCF, Agena, CSV, XLSX, JSON, HL7/FHIR & custom imports
002.
Go live in 5–7 days, not months
003.
API, EHR, HL7 ORU, FHIR R4 & CDS Hooks integrations
004.
Branded provider, patient and living passport delivery
004.
LIVING EVIDENCE INFRASTRUCTURE
PGx Reports That Stay Alive After Release
SignalPGx stores the genotype as a permanent clinical asset, then continuously re-evaluates it when guidance changes, medications are added, or new risks emerge — raising alerts, updating insights, and connecting results back into clinical workflows.


WHAT SIGNALPGx GENERATES
001.
Living reanalysis when guidance or medications change
002.
CPIC, DPWG, FDA, PharmGKB & multi-source evidence graph
003.
FHIR R4, HL7 ORU & CDS Hooks for EHR workflows
004.
Audit trails, QC review, RBAC & medical-director release.

(WDX® — 03)
OUR SERVICES
PGx Reporting Services
Four core capabilities designed to help labs launch, scale, and deliver physician-ready pharmacogenomic reports.
001.
PHARMACOGENOMIC INTELLIGENCE LAYER
From Genotype to Evidence-Graded PGx Reports
SignalPGx turns VCF, Agena MassARRAY plates, flexible instrument CSVs, and custom lab files into branded, evidence-graded PGx reports with SignalAI interpretation, medication intelligence, and medical-director review built in.


WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports
002.
50 pharmacogenes and ~950 guided medications
003.
15+ evidence sources fused into one intelligence graph
004.
Medical-director review, release and audit trail
002.
MEDICATION INTELLIGENCE SIMULATION
Test Medication Risk Before It Reaches the Patient
SignalPGx uses SignalAI and the Medication Intelligence Graph to model add, remove, or swap scenarios, recompute phenoconversion, detect drug-drug-gene interactions, and surface genotype-aware safer alternatives.


WHAT SIGNALPGx GENERATES
001.
Add / remove / swap medication scenarios
002.
Phenoconversion and drug-drug-gene interactions
003.
Genotype-aware dosing and safer alternatives
004.
SignalAI cited review with evidence refusal guardrails
003.
WHITE-LABEL LAB INFRASTRUCTURE
Launch Branded PGx Reporting in 5–7 Days
SignalPGx gives labs the reporting engine, file intake layer, SignalAI review workflow, branded report suite, and provider delivery infrastructure needed to launch PGx under their own brand without months of software buildout.


WHAT SIGNALPGx GENERATES
001.
Multi-format PGx engine: VCF, Agena, CSV, XLSX, JSON, HL7/FHIR & custom imports
002.
Go live in 5–7 days, not months
003.
API, EHR, HL7 ORU, FHIR R4 & CDS Hooks integrations
004.
Branded provider, patient and living passport delivery
004.
LIVING EVIDENCE INFRASTRUCTURE
PGx Reports That Stay Alive After Release
SignalPGx stores the genotype as a permanent clinical asset, then continuously re-evaluates it when guidance changes, medications are added, or new risks emerge — raising alerts, updating insights, and connecting results back into clinical workflows.


WHAT SIGNALPGx GENERATES
001.
Living reanalysis when guidance or medications change
002.
CPIC, DPWG, FDA, PharmGKB & multi-source evidence graph
003.
FHIR R4, HL7 ORU & CDS Hooks for EHR workflows
004.
Audit trails, QC review, RBAC & medical-director release.

(WDX® — 03)
OUR SERVICES
PGx Reporting Services
Сore capabilities used to design, deploy, and scale AI systems.
001.
PHARMACOGENOMIC INTELLIGENCE LAYER
From Genotype to Evidence-Graded PGx Reports
SignalPGx turns VCF, Agena MassARRAY plates, flexible instrument CSVs, and custom lab files into branded, evidence-graded PGx reports with SignalAI interpretation, medication intelligence, and medical-director review built in.


001.
Branded summary & comprehensive PGx reports
002.
50 pharmacogenes and ~950 guided medications
003.
15+ evidence sources fused into one intelligence graph
004.
Medical-director review, release and audit trail
002.
MEDICATION INTELLIGENCE SIMULATION
Test Medication Risk Before It Reaches the Patient
SignalPGx uses SignalAI and the Medication Intelligence Graph to model add, remove, or swap scenarios, recompute phenoconversion, detect drug-drug-gene interactions, and surface genotype-aware safer alternatives.


001.
Add / remove / swap medication scenarios
002.
Phenoconversion and drug-drug-gene interactions
003.
Genotype-aware dosing and safer alternatives
004.
SignalAI cited review with evidence refusal guardrails
003.
WHITE-LABEL LAB INFRASTRUCTURE
Launch Branded PGx Reporting in 5–7 Days
SignalPGx gives labs the reporting engine, file intake layer, SignalAI review workflow, branded report suite, and provider delivery infrastructure needed to launch PGx under their own brand without months of software buildout.


001.
Multi-format PGx engine: VCF, Agena, CSV, XLSX, JSON, HL7/FHIR & custom imports
002.
Go live in 5–7 days, not months
003.
API, EHR, HL7 ORU, FHIR R4 & CDS Hooks integrations
004.
Branded provider, patient and living passport delivery
004.
LIVING EVIDENCE INFRASTRUCTURE
PGx Reports That Stay Alive After Release
SignalPGx stores the genotype as a permanent clinical asset, then continuously re-evaluates it when guidance changes, medications are added, or new risks emerge — raising alerts, updating insights, and connecting results back into clinical workflows.


001.
Living reanalysis when guidance or medications change
002.
CPIC, DPWG, FDA, PharmGKB & multi-source evidence graph
003.
FHIR R4, HL7 ORU & CDS Hooks for EHR workflows
004.
Audit trails, QC review, RBAC & medical-director release.

1
2
3
4
/4
(WDX® — 03)
OUR SERVICES
PGx Reporting Services
Four core capabilities designed to help labs launch, scale, and deliver physician-ready pharmacogenomic reports.
001.
PHARMACOGENOMIC INTELLIGENCE LAYER
From Genotype to Evidence-Graded PGx Reports
SignalPGx turns VCF, Agena MassARRAY plates, flexible instrument CSVs, and custom lab files into branded, evidence-graded PGx reports with SignalAI interpretation, medication intelligence, and medical-director review built in.


WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports
002.
50 pharmacogenes and ~950 guided medications
003.
15+ evidence sources fused into one intelligence graph
004.
Medical-director review, release and audit trail
002.
MEDICATION INTELLIGENCE SIMULATION
Test Medication Risk Before It Reaches the Patient
SignalPGx uses SignalAI and the Medication Intelligence Graph to model add, remove, or swap scenarios, recompute phenoconversion, detect drug-drug-gene interactions, and surface genotype-aware safer alternatives.


WHAT SIGNALPGx GENERATES
001.
Add / remove / swap medication scenarios
002.
Phenoconversion and drug-drug-gene interactions
003.
Genotype-aware dosing and safer alternatives
004.
SignalAI cited review with evidence refusal guardrails
003.
WHITE-LABEL LAB INFRASTRUCTURE
Launch Branded PGx Reporting in 5–7 Days
We design and build custom AI systems tailored to your operations — from internal AI tools to decision-support platforms used by teams daily.


WHAT SIGNALPGx GENERATES
001.
Multi-format PGx engine: VCF, Agena, CSV, XLSX, JSON, HL7/FHIR & custom imports
002.
Go live in 5–7 days, not months
003.
API, EHR, HL7 ORU, FHIR R4 & CDS Hooks integrations
004.
Branded provider, patient and living passport delivery
004.
LIVING EVIDENCE INFRASTRUCTURE
PGx Reports That Stay Alive After Release
SignalPGx stores the genotype as a permanent clinical asset, then continuously re-evaluates it when guidance changes, medications are added, or new risks emerge — raising alerts, updating insights, and connecting results back into clinical workflows.


WHAT SIGNALPGx GENERATES
001.
Living reanalysis when guidance or medications change
002.
CPIC, DPWG, FDA, PharmGKB & multi-source evidence graph
003.
FHIR R4, HL7 ORU & CDS Hooks for EHR workflows
004.
Audit trails, QC review, RBAC & medical-director release.

1
2
3
4
/4
(WDX® — 03)
PGX REPORTING SERVICES
Our Services
Four core capabilities designed to help labs launch, scale, and deliver physician-ready pharmacogenomic reports.
001.
PHARMACOGENOMIC INTELLIGENCE LAYER
From Genotype to Evidence-Graded PGx Reports
SignalPGx turns VCF, Agena MassARRAY plates, flexible instrument CSVs, and custom lab files into branded, evidence-graded PGx reports with SignalAI interpretation, medication intelligence, and medical-director review built in.


WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports
002.
50 pharmacogenes and ~950 guided medications
003.
15+ evidence sources fused into one intelligence graph
004.
Medical-director review, release and audit trail
002.
MEDICATION INTELLIGENCE SIMULATION
Test Medication Risk Before It Reaches the Patient
SignalPGx uses SignalAI and the Medication Intelligence Graph to model add, remove, or swap scenarios, recompute phenoconversion, detect drug-drug-gene interactions, and surface genotype-aware safer alternatives.


WHAT SIGNALPGx GENERATES
001.
Add / remove / swap medication scenarios
002.
Phenoconversion and drug-drug-gene interactions
003.
Genotype-aware dosing and safer alternatives
004.
SignalAI cited review with evidence refusal guardrails
003.
WHITE-LABEL LAB INFRASTRUCTURE
Launch Branded PGx Reporting in 5–7 Days
We design and build custom AI systems tailored to your operations — from internal AI tools to decision-support platforms used by teams daily.


WHAT SIGNALPGx GENERATES
001.
Multi-format PGx engine: VCF, Agena, CSV, XLSX, JSON, HL7/FHIR & custom imports
002.
Go live in 5–7 days, not months
003.
API, EHR, HL7 ORU, FHIR R4 & CDS Hooks integrations
004.
Branded provider, patient and living passport delivery
004.
LIVING EVIDENCE INFRASTRUCTURE
PGx Reports That Stay Alive After Release
SignalPGx stores the genotype as a permanent clinical asset, then continuously re-evaluates it when guidance changes, medications are added, or new risks emerge — raising alerts, updating insights, and connecting results back into clinical workflows.


WHAT SIGNALPGx GENERATES
001.
Living reanalysis when guidance or medications change
002.
CPIC, DPWG, FDA, PharmGKB & multi-source evidence graph
003.
FHIR R4, HL7 ORU & CDS Hooks for EHR workflows
004.
Audit trails, QC review, RBAC & medical-director release.
(spx® — 04)
DEFENSIBILITY LAYER
The SignalPGx Moat
The SignalPGx Moat
The SignalPGx Moat
Most PGx platforms generate static reports. SignalPGx compounds into a living
intelligence layer built from evidence, outcomes, alerts, integrations, and reusable lab infrastructure.
Most PGx platforms generate static reports. SignalPGx compounds into a living
intelligence layer built from evidence, outcomes, alerts, integrations, and reusable lab infrastructure.
2025
Medication Intelligence Graph
A clinical evidence graph fusing CPIC, DPWG, FDA labels, PharmGKB, RxNorm, PharmVar, ClinVar, ClinGen, population frequencies, adverse-event signals, and drug–gene relationships into one PGx intelligence layer.
Industry
15+ integrated evidence sources
SERVICE USED
Evidence Interpretation, Report Automation
Challenge
SignalAI + RAG + knowledge graph + living reanalysis
Technology Stacks
CPIC
Logix
FDA
RxNorm
Synth
HGNC
2025
Medication Intelligence Graph
A clinical evidence graph fusing CPIC, DPWG, FDA labels, PharmGKB, RxNorm, PharmVar, ClinVar, ClinGen, population frequencies, adverse-event signals, and drug–gene relationships into one PGx intelligence layer.
Industry
15+ integrated evidence sources
SERVICE USED
Evidence Interpretation, Report Automation
Challenge
Turnaround slowed as report volume increased
Technology Stacks
2025
Medication Intelligence Graph
SignalPGx fuses CPIC, DPWG, FDA labels, PharmGKB, PharmVar, ClinVar and RxNorm into one clinical evidence graph behind every medication recommendation.
Industry
15+ integrated evidence sources
SERVICES
Evidence Interpretation, Report Automation
Challenge
Turnaround slowed as report volume increased
Technology Stacks
2025
Medication Intelligence Graph
SignalPGx fuses CPIC, DPWG, FDA labels, PharmGKB, PharmVar, ClinVar and RxNorm into one clinical evidence graph behind every medication recommendation.
Industry
15+ integrated evidence sources
SERVICE USED
Evidence Interpretation, Report Automation
Challenge
Turnaround slowed as report volume increased
Technology Stacks
2025
Medication Intelligence Graph
SignalPGx fuses CPIC, DPWG, FDA labels, PharmGKB, PharmVar, ClinVar and RxNorm into one clinical evidence graph behind every medication recommendation.
Industry
15+ integrated evidence sources
SERVICE USED
Evidence Interpretation, Report Automation
Challenge
Turnaround slowed as report volume increased
Technology Stacks
(spx® — 05)
More cases

Play
Inside SignalPGx
1:42 min overview

Play
Inside SignalPGx
1:42 min overview
ACTIVITY
Operational
Decisions
+
Automated decisions
across deployed AI systems
+15%
jun.
+35%
jul.
+53%
aug.
Benchmark
System
Recovery
%
Faster operational recovery
To launch branded
PGx REPORTING
after AI decision automation
No hype. Just systems
Clarity beats automation
Decisions over demos
Designed for messy reality
Systems that hold under pressure
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/4
(SPX® — 06)
Process
Execution Flow
A structured process used to design, deploy, and scale AI systems across real operational environments.
001.
Audit
System Audit & Discovery
We analyze how the system actually operates across workflows, data, and decision points. This step identifies constraints and opportunities before any AI or automation is introduced.
WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports and handoffs
002.
Data sources, ownership, and consistency
003.
15+ evidence sources fused into one intelligence graph
004.
Existing tools, integrations, and constraints
Technology Stacks
CPIC
RxNorm
Synth
FDA
002.
AUTOMATION
Automation Design & Agents
We design intelligent automation systems and AI agents tailored to your operational workflows. This step translates audit insights into executable automation architecture and controlled agent behavior.
WHAT SIGNALPGx GENERATES
001.
Automation-ready workflows and task clusters
002.
Decision trees, escalation paths, and guardrails
003.
System APIs and integration surface
004.
Human-in-the-loop control mechanisms
Technology Stacks
Kortx
Strat
HGNC
CPIC
003.
ARCHITECTURE
AI Strategy & Technical Architecture
We define the long-term AI direction aligned with business priorities. This step ensures that every AI initiative fits within a scalable, secure, and economically viable architecture.
WHAT SIGNALPGx GENERATES
001.
Strategic objectives and ROI potential
002.
Data infrastructure maturity
003.
Build vs. buy vs. hybrid scenarios
004.
Governance, compliance, and risk models
Technology Stacks
CPIC
Nexis
Atica
LOINC
004.
INFRASTRUCTURE
Data Infrastructure & Foundations
We build the structured data layer required for reliable AI systems. This step transforms fragmented data into consistent, model-ready infrastructure.
WHAT SIGNALPGx GENERATES
001.
Data sources and ingestion pipelines
002.
Data quality, gaps, and normalization
003.
Storage architecture and retrieval performance
004.
Security, privacy, and access control
Technology Stacks
Logix
Axiom
Lumen
RxNorm
(SPX® — 06)
Process
Execution Flow
A structured process used to design, deploy, and scale AI systems across real operational environments.
001.
Audit
System Audit & Discovery
We analyze how the system actually operates across workflows, data, and decision points. This step identifies constraints and opportunities before any AI or automation is introduced.
WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports and handoffs
002.
Data sources, ownership, and consistency
003.
15+ evidence sources fused into one intelligence graph
004.
Existing tools, integrations, and constraints
Technology Stacks
CPIC
RxNorm
Synth
FDA

1
2
3
4
/4
002.
AUTOMATION
Automation Design & Agents
We design intelligent automation systems and AI agents tailored to your operational workflows. This step translates audit insights into executable automation architecture and controlled agent behavior.
WHAT SIGNALPGx GENERATES
001.
Automation-ready workflows and task clusters
002.
Decision trees, escalation paths, guardrails
003.
System APIs and integration surface
004.
Human-in-the-loop control mechanisms
Technology Stacks
Kortx
Strat
HGNC
CPIC

1
2
3
4
/4
003.
ARCHITECTURE
AI Strategy & Technical Architecture
We define the long-term AI direction aligned with business priorities. This step ensures that every AI initiative fits within a scalable, secure, and economically viable architecture.
WHAT SIGNALPGx GENERATES
001.
Strategic objectives and ROI potential
002.
Data infrastructure maturity
003.
Build vs. buy vs. hybrid scenarios
004.
Governance, compliance, and risk models
Technology Stacks
CPIC
Nexis
Atica
LOINC

1
2
3
4
/4
004.
INFRASTRUCTURE
Data Infrastructure & Foundations
We build the structured data layer required for reliable AI systems. This step transforms fragmented data into consistent, model-ready infrastructure.
WHAT SIGNALPGx GENERATES
001.
Data sources and ingestion pipelines
002.
Data quality, gaps, and normalization
003.
Storage architecture and retrieval performance
004.
Security, privacy, and access control
Technology Stacks
Logix
Axiom
Lumen
RxNorm

1
2
3
4
/4
(SPX® — 06)
Process
Execution Flow
A structured process used to design, deploy, and scale AI systems across operational environments.
001.
Audit
System Audit & Discovery
We analyze workflows, data, and decision points to identify constraints and opportunities before implementation begins.
001.
Branded summary & comprehensive PGx reports and handoffs
002.
Data sources, ownership, and consistency
003.
15+ evidence sources fused into one intelligence graph
004.
Tools, integrations, and constraints
Technology Stacks

1
2
3
4
/4
002.
AUTOMATION
Automation Design & Agents
We design AI agents and automation systems tailored to your workflows, turning audit insights into practical automation architecture.
001.
Automation-ready workflows and task clusters
002.
Decision trees, and guardrails
003.
System APIs and integration surface
004.
Human-in-the-loop control mechanisms
Technology Stacks

1
2
3
4
/4
003.
ARCHITECTURE
AI Strategy & Technical Architecture
We define a long-term AI strategy aligned with business goals, ensuring every initiative supports scalable and sustainable growth.
001.
Strategic objectives and ROI potential
002.
Data infrastructure maturity
003.
Build vs. buy vs. hybrid scenarios
004.
Governance, compliance, and risk models
Technology Stacks

1
2
3
4
/4
004.
INFRASTRUCTURE
Data Infrastructure & Foundations
We build the structured data layer required for reliable AI systems. We transform fragmented data into consistent, model-ready infrastructure.
001.
Data sources and ingestion pipelines
002.
Data quality, gaps, and normalization
003.
Storage architecture and performance
004.
Security, privacy, and access control
Technology Stacks

1
2
3
4
/4
1
2
3
4
/4
(SPX® — 06)
Process
Execution Flow
A structured process used to design, deploy, and scale AI systems across real operational environments.
001.
Audit
System Audit & Discovery
We analyze workflows, data, and decision points to identify constraints and opportunities before implementation begins.
WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports and handoffs
002.
Data sources, ownership, and consistency
003.
15+ evidence sources fused into one intelligence graph
004.
Existing tools, integrations, and constraints
Technology Stacks
CPIC
RxNorm
Synth
FDA
002.
AUTOMATION
Automation Design & Agents
We design AI agents and automation systems tailored to your workflows, turning audit insights into practical automation architecture.
WHAT SIGNALPGx GENERATES
001.
Automation-ready workflows and task clusters
002.
Decision trees, escalation paths, and guardrails
003.
System APIs and integration surface
004.
Human-in-the-loop control mechanisms
Technology Stacks
Kortx
Strat
HGNC
CPIC
003.
ARCHITECTURE
AI Strategy & Technical Architecture
We define a long-term AI strategy aligned with business goals, ensuring every initiative supports scalable and sustainable growth.
WHAT SIGNALPGx GENERATES
001.
Strategic objectives and ROI potential
002.
Data infrastructure maturity
003.
Build vs. buy vs. hybrid scenarios
004.
Governance, compliance, and risk models
Technology Stacks
CPIC
Nexis
Atica
LOINC
004.
INFRASTRUCTURE
Data Infrastructure & Foundations
We build the structured data layer required for reliable AI systems. This step transforms fragmented data into consistent, model-ready infrastructure.
WHAT SIGNALPGx GENERATES
001.
Data sources and ingestion pipelines
002.
Data quality, gaps, and normalization
003.
Storage architecture and retrieval performance
004.
Security, privacy, and access control
Technology Stacks
Logix
Axiom
Lumen
RxNorm
1
2
3
4
/4
(SPX® — 06)
Process
Execution Flow
A structured process used to design, deploy, and scale AI systems across real operational environments.
001.
Audit
System Audit & Discovery
We analyze workflows, data, and decision points to identify constraints and opportunities before implementation begins.
WHAT SIGNALPGx GENERATES
001.
Branded summary & comprehensive PGx reports and handoffs
002.
Data sources, ownership, and consistency
003.
15+ evidence sources fused into one intelligence graph
004.
Existing tools, integrations, and constraints
Technology Stacks
CPIC
RxNorm
Synth
FDA
002.
AUTOMATION
Automation Design & Agents
We design AI agents and automation systems tailored to your workflows, turning audit insights into practical automation architecture.
WHAT SIGNALPGx GENERATES
001.
Automation-ready workflows and task clusters
002.
Decision trees, escalation paths, and guardrails
003.
System APIs and integration surface
004.
Human-in-the-loop control mechanisms
Technology Stacks
Kortx
Strat
HGNC
CPIC
003.
ARCHITECTURE
AI Strategy & Technical Architecture
We define a long-term AI strategy aligned with business goals, ensuring every initiative supports scalable and sustainable growth.
WHAT SIGNALPGx GENERATES
001.
Strategic objectives and ROI potential
002.
Data infrastructure maturity
003.
Build vs. buy vs. hybrid scenarios
004.
Governance, compliance, and risk models
Technology Stacks
CPIC
Nexis
Atica
LOINC
004.
INFRASTRUCTURE
Data Infrastructure & Foundations
We build the structured data layer required for reliable AI systems. This step transforms fragmented data into consistent infrastructure.
WHAT SIGNALPGx GENERATES
001.
Data sources and ingestion pipelines
002.
Data quality, gaps, and normalization
003.
Storage architecture and retrieval performance
004.
Security, privacy, and access control
Technology Stacks
Logix
Axiom
Lumen
RxNorm
What We Deliver
(®)
(spx® — 07)
SYSTEM OUTPUT
We design and build AI systems that operate
inside real workflows — from idea to production.
© ‒ 001.
Operational AI Expertise
We specialize in AI systems designed for real operational environments — not experiments or isolated prototypes.
© ‒ 001.
Operational AI Expertise
We specialize in AI systems designed for real operational environments — not experiments or isolated prototypes.
© ‒ 001.
Operational AI Expertise
We build reliable AI systems for real-world operations.
© ‒ 001.
Operational AI Expertise
We build reliable AI systems for real-world operations.
SignalPGx
SignalPGx
© ‒ 002.
Systems That Actually Ship
Our work focuses on production-ready AI tools that integrate with existing infrastructure and workflows.
© ‒ 002.
Systems That Actually Ship
Our work focuses on production-ready AI tools that integrate with existing infrastructure and workflows.
© ‒ 002.
Systems That Actually Ship
Production-ready AI tools built for existing systems and workflows.
© ‒ 002.
Systems That Actually Ship
Production-ready AI tools built for existing systems and workflows.
© ‒ 003.
Deep Technical Ownership
From architecture to deployment, our team builds and operates the systems we design.
© ‒ 003.
Deep Technical Ownership
From architecture to deployment, our team builds and operates the systems we design.
© ‒ 003.
Deep Technical Ownership
We build and operate every system we design.
© ‒ 004.
Real Business Impact
Every system is built to improve measurable outcomes — operational speed, reliability, and decision quality.
© ‒ 004.
Real Business Impact
Every system is built to improve measurable outcomes — operational speed, reliability, and decision quality.
© ‒ 005.
Clear Collaboration
Transparent communication, defined milestones, and full visibility across every stage of the project.
© ‒ 005.
Clear Collaboration
Transparent communication, defined milestones, and full visibility across every stage of the project.
© ‒ 005.
Clear Collaboration
Transparent communication and full visibility at every stage.
© ‒ 005.
Clear Collaboration
Transparent communication and full visibility at every stage.
(spx® — 08)
OUR JOURNEY
Engineering systems that turn
complex work into automation
Engineering systems
that turn complex work into automation
From early automation tools to building
production AI systems used by growing companies.
2018 — 2019
Small Team Beginnings
We started as a small engineering team focused on automation and internal tools.
2019 — 2021
First AI Projects
Early client projects focused on AI-powered workflow automation.
2021 — 2023
Systems Expansion
Our work expanded into full AI systems and operational infrastructure.
2023 — Present
Operational AI Studio
Today we design production AI systems used across multiple industries.
2018 — 2019
Small Team Beginnings
We started as a small engineering team focused on automation and internal tools.
2019 — 2021
First AI Projects
Early client projects focused on AI-powered workflow automation.
2021 — 2023
Systems Expansion
Our work expanded into full AI systems and operational infrastructure.
2023 — Present
Operational AI Studio
Today we design production AI systems used across multiple industries.
2018 — 2019
Small Team Beginnings
We started as a small engineering team focused on automation and internal tools.
2019 — 2021
First AI Projects
Early client projects focused on AI-powered workflow automation.
2021 — 2023
Systems Expansion
Our work expanded into full AI systems and operational infrastructure.
2023 — Present
Operational AI Studio
Today we design production AI systems used across multiple industries.
2018 — 2019
Small Team Beginnings
We started as a small team focused on automation and internal tools.
2019 — 2021
First AI Projects
Early client projects focused on AI-powered workflow automation.
2021 — 2023
Systems Expansion
Our work expanded into full AI systems and operational infrastructure.
2023 — Present
Operational AI Studio
Today we design production AI systems used across multiple industries.
2018 — 2019
Small Team Beginnings
We started as a small team focused on automation and internal tools.
2019 — 2021
First AI Projects
Early client projects focused on AI-powered workflow automation.
2021 — 2023
Systems Expansion
Our work expanded into full AI systems and operational infrastructure.
2023 — Present
Operational AI Studio
Today we design production AI systems used across multiple industries.













Helping teams transform
repetitive work into AI systems
From early exploration to deploying AI systems that support real operational workflows.









Helping teams transform
repetitive work into AI systems
From early exploration to deploying AI systems that support real operational workflows.





Helping teams transform
repetitive work into AI systems
From early exploration to deploying AI systems that support real operational workflows.













Helping teams transform
repetitive work into AI systems
From early exploration to deploying AI systems that support real operational workflows.
No hype. Just systems
Clarity beats automation
Decisions over demos
Designed for messy reality
Systems that hold under pressure
(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
1
2
3
4
5
/5
AI Engineers
A small team of engineers and researchers building production-grade AI systems for real-world operations.





(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building AI systems.
(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
1
2
3
4
5
/5
AI Engineers
A small team of engineers and researchers building production-grade AI systems for real-world operations.





(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
1
2
3
4
5
/5
AI Engineers
A small team of engineers and researchers building production-grade AI systems for real-world operations.





(spx® — 10)
ENGAGEMENT MODELS
Access plans
Access plans
Access plans
Flexible engagement models for teams
exploring or scaling AI systems.
SignalPGx brought structure and clarity to our AI roadmap and helped us deploy systems that actually work in production.

David Ramirez
Founder & CEO, SignalPGx
SignalPGx brought structure and clarity to our AI roadmap and helped us deploy systems that actually work in production.

David Ramirez
Founder & CEO, SignalPGx
© ‒ 001.
Discovery & Strategy
We analyze your systems, workflows, and data landscape to identify high-impact AI opportunities and define the technical direction.
from
$7000
$
/project
Timeframe:
Typically delivered in 2–3 weeks
What’s included:
Analysis of existing processes and manual operations across key teams
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Design of data pipelines and model infrastructure
© ‒ 001.
Discovery & Strategy
We analyze your systems, workflows, and data landscape to identify high-impact AI opportunities and define the technical direction.
from
$7000
$
/project
Timeframe:
Typically delivered in 2–3 weeks
What’s included:
Analysis of existing processes and manual operations across key teams
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Design of data pipelines and model infrastructure
© ‒ 001.
Discovery & Strategy
We analyze your systems, workflows, and data to identify high-impact AI opportunities.
from
$7000
$
/project
Timeframe:
2–3 weeks
What’s included:
Process Workflow Analysis
AI Opportunity Identification
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Data Structure Review
System Architecture Definition
Pipeline Infrastructure Design
© ‒ 001.
Discovery & Strategy
We analyze your systems, workflows, and data landscape to identify high-impact AI opportunities.
from
$7000
$
/project
Timeframe:
Typically delivered in 2–3 weeks
What’s included:
Analysis of existing processes and manual operations
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Design of data pipelines and model infrastructure
© ‒ 001.
Discovery & Strategy
We analyze your systems, workflows, and data landscape to identify high-impact AI opportunities
from
$7000
$
/project
Timeframe:
Typically delivered in 2–3 weeks
What’s included:
Analysis of existing processes
Identification of high-impact AI
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure
Definition of AI system architecture
Design of data pipelines
© ‒ 002.
System Design
Designing the architecture, data pipelines, and technical foundation required to deploy AI systems in production.
from
$9000
$
/project
Timeframe:
Typically delivered in 3–5 weeks
What’s included:
Analysis of existing processes and manual operations across key teams
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines and model infrastructure
© ‒ 002.
System Design
Designing the architecture, data pipelines, and technical foundation required to deploy AI systems in production.
from
$9000
$
/project
Timeframe:
Typically delivered in 3–5 weeks
What’s included:
Analysis of existing processes and manual operations across key teams
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines and model infrastructure
© ‒ 002.
System Design
Designing the architecture and technical foundation required to deploy AI systems.
from
$9000
$
/project
Timeframe:
3–5 weeks
What’s included:
Process Workflow Analysis
AI Opportunity Identification
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Data Structure Review
System Architecture Definition
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Pipeline Infrastructure Design
© ‒ 002.
System Design
Designing the architecture, data pipelines, and technical foundation required to deploy AI systems in production.
from
$9000
$
/project
Timeframe:
Typically delivered in 3–5 weeks
What’s included:
Analysis of existing processes and manual operations across
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines and model infrastructure
© ‒ 002.
System Design
Designing the architecture and data pipelines required to deploy AI systems
from
$9000
$
/project
Timeframe:
Typically delivered in 3–5 weeks
What’s included:
Analysis of existing processes
Identification of high-impact AI
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure
Definition of AI system architecture
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines
© ‒ 003.
Deployment & Integration
Building, integrating, and deploying AI systems directly into your existing tools, workflows, and operations.
from
$15000
$
/project
Timeframe:
Typically delivered in 4–8 weeks
What’s included:
Analysis of existing processes and manual operations across key teams
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines and model infrastructure
© ‒ 003.
Deployment & Integration
Building, integrating, and deploying AI systems directly into your existing tools, workflows, and operations.
from
$15000
$
/project
Timeframe:
Typically delivered in 4–8 weeks
What’s included:
Analysis of existing processes and manual operations across key teams
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines and model infrastructure
© ‒ 003.
Deployment & Integration
Building, integrating, and deploying AI systems directly into your existing tools and workflows.
from
$15000
$
/project
Timeframe:
4–8 weeks
What’s included:
Process Workflow Analysis
AI Opportunity Identification
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Data Structure Review
System Architecture Definition
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Pipeline Infrastructure Design
© ‒ 003.
Deployment & Integration
Building, integrating, and deploying AI systems directly into your existing tools, workflows, and operations.
from
$15000
$
/project
Timeframe:
Typically delivered in 4–8 weeks
What’s included:
Analysis of existing processes and manual operations
Identification of high-impact AI and automation opportunities
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure and integration readiness
Definition of AI system architecture and technical direction
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines and model infrastructure
© ‒ 003.
Deployment & Integration
Building, integrating, and deploying AI systems directly into your existing tools.
from
$15000
$
/project
Timeframe:
Typically delivered in 4–8 weeks
What’s included:
Analysis of existing processes
Identification of high-impact AI
Identifying high-impact AI opportunities across operations, workflows, and data processes where automation can deliver measurable value.
Review of data structure
Definition of AI system architecture
Defining system architecture, model strategy, and integration approach required to deploy reliable AI solutions in production.
Design of data pipelines
Governed Architecture
Governed Architecture
Orchestrated
Governed Architecture
(spx® — 11)
Insights & Research
Recent articles
Recent articles
Recent articles
Notes on AI systems, architecture decisions,
and lessons from real deployments.
(spx® — 12)
Our newsletters
Stay in the loop
No hype. Just systems
Clarity beats automation
Decisions over demos
Designed for messy reality
Systems that hold under pressure

(spx® — 13)
frequently asked questions
Signal,
not noise.
Core Questions
Clear, factual answers about how SignalPGx
turns genotyping into living PGx reports.
Clear, factual answers about how SignalPGx turns genotyping into living PGx reports.
001.
Is SignalPGx a diagnostic test or does it replace my doctor?
SignalPGx is pharmacogenomic decision-support and reporting software, not a diagnostic test, and it is not FDA-cleared or FDA-approved. It never replaces the physician: every report is reviewed and released by the lab's medical director, and final prescribing stays with the ordering clinician.
001.
Is SignalPGx a diagnostic test or does it replace my doctor?
SignalPGx is pharmacogenomic decision-support and reporting software, not a diagnostic test, and it is not FDA-cleared or FDA-approved. It never replaces the physician: every report is reviewed and released by the lab's medical director, and final prescribing stays with the ordering clinician.
002.
What evidence and drug/gene coverage does SignalPGx use?
SignalPGx bases every PGx recommendation on evidence-graded guidance across 50 pharmacogenes and about 950 medications, fused from 15+ curated sources including CPIC, FDA pharmacogenetic associations and drug labeling, and DailyMed. No result is released without lab medical-director review.
002.
What evidence and drug/gene coverage does SignalPGx use?
SignalPGx bases every PGx recommendation on evidence-graded guidance across 50 pharmacogenes and about 950 medications, fused from 15+ curated sources including CPIC, FDA pharmacogenetic associations and drug labeling, and DailyMed. No result is released without lab medical-director review.
002.
How long does it take to see ROI?
SignalPGx bases every PGx recommendation on evidence-graded guidance across 50 pharmacogenes and about 950 medications, fused from 15+ curated sources including CPIC, FDA pharmacogenetic associations and drug labeling, and DailyMed. No result is released without lab medical-director review.
003.
How does SignalPGx keep PGx reports up to date?
SignalPGx keeps reports current through Living Reports, which automatically re-analyze a patient's results when guidelines or their medication list change. When new evidence affects a prior result, the platform flags the report and alerts the lab so a medical director can review and reissue it.
003.
How does SignalPGx keep PGx reports up to date?
SignalPGx keeps reports current through Living Reports, which automatically re-analyze a patient's results when guidelines or their medication list change. When new evidence affects a prior result, the platform flags the report and alerts the lab so a medical director can review and reissue it.
003.
Can we integrate AI agents with our existing software stack?
SignalPGx keeps reports current through Living Reports, which automatically re-analyze a patient's results when guidelines or their medication list change. When new evidence affects a prior result, the platform flags the report and alerts the lab so a medical director can review and reissue it.
003.
Can we integrate AI agents with our existing stack?
SignalPGx keeps reports current through Living Reports, which automatically re-analyze a patient's results when guidelines or their medication list change. When new evidence affects a prior result, the platform flags the report and alerts the lab so a medical director can review and reissue it.
004.
Is SignalPGx HIPAA compliant and how is data secured?
Yes. SignalPGx is HIPAA- and GDPR-compliant, hosted on secured AWS infrastructure. Data is protected with encryption in transit and at rest, role-based access control (RBAC), and strict tenant isolation that keeps each lab's data fully separate, all within CLIA-certified laboratory workflows and backed by a complete audit trail of every report action.
004.
Is SignalPGx HIPAA compliant and how is data secured?
Yes. SignalPGx is HIPAA- and GDPR-compliant, hosted on secured AWS infrastructure. Data is protected with encryption in transit and at rest, role-based access control (RBAC), and strict tenant isolation that keeps each lab's data fully separate, all within CLIA-certified laboratory workflows and backed by a complete audit trail of every report action.
005.
How do labs launch and white-label SignalPGx on an EHR?
Most labs go live on SignalPGx in 5-7 days, delivering fully white-labeled provider reports, patient reports, and a revocable QR Patient Passport under their own brand. It connects to EHRs through FHIR R4, HL7 ORU, CDS Hooks, and SMART on FHIR.
005.
How do labs launch and white-label SignalPGx on an EHR?
Most labs go live on SignalPGx in 5-7 days, delivering fully white-labeled provider reports, patient reports, and a revocable QR Patient Passport under their own brand. It connects to EHRs through FHIR R4, HL7 ORU, CDS Hooks, and SMART on FHIR.
(spx® — 14)
OUR CONTACT
Let's talk
Let's talk
Let's talk
Bring your lab, your genotyping data, or your questions.
We’ll show you how to launch branded PGx reports, fast.
Bring your lab, your genotyping data, or your questions.
We’ll show you how to launch branded PGx reports.
info@signalpgx.com
Send message
Book a Call
Partner with us
Send message
Book a Call
Partner with us
No hype. Just systems
No hype. Just systems
No hype. Just systems
Clarity beats automation
Clarity beats automation
Clarity beats automation
Decisions over demos
Decisions over demos
Decisions over demos
Designed for messy reality
Designed for messy reality
Designed for messy reality
Systems that hold under pressure
Systems that hold under pressure
Systems that hold under pressure

(spx® — 15)
OUR PRINCIPLES
What
We Believe
Core Beliefs
We turn genotyping results into
living, evidence-graded PGx reports.
We turn genotyping results into living, evidence-graded PGx reports.
We believe technology should solve real problems, not create new ones. If it doesn’t make the work simpler, faster, or clearer — it doesn’t belong.
We believe technology should solve real problems, not create new ones. If it doesn’t make the work simpler, faster, or clearer — it doesn’t belong.
We believe technology should solve real problems, not create new ones. If it doesn’t make the work simpler, faster, or clearer — it doesn’t belong.
We believe technology should solve real problems, not create new ones. If it doesn’t make the work simpler, faster, or clearer — it doesn’t belong.
We believe technology should solve real problems, not create new ones. If it doesn’t make the work simpler, faster, or clearer — it doesn’t belong.
Every SignalPGx report is graded against CPIC, FDA, and DailyMed, then released under your lab’s brand after medical-director review. Living Reports reanalyze it the day guidance or a patient’s meds change.
Every SignalPGx report is graded against CPIC, FDA, and DailyMed, then released under your lab’s brand after medical-director review. Living Reports reanalyze it the day guidance or a patient’s meds change.
It’s to design systems that remain understandable,
explainable, and controllable — even when things go wrong.
Every SignalPGx report is graded against CPIC, FDA, and DailyMed, then released under your lab’s brand after medical-director review. Living Reports reanalyze it the day guidance or a patient’s meds change.
Every SignalPGx report is graded against CPIC, FDA, and DailyMed, then released under your lab’s brand after medical-director review. Living Reports reanalyze it the day guidance or a patient’s meds change.
when things go wrong.
Every SignalPGx report is graded against CPIC, FDA, and DailyMed, then released under your lab’s brand after medical-director review. Living Reports reanalyze it the day guidance or a patient’s meds change.
It’s to design systems that remain understandable,
explainable, and controllable — even when things go wrong.













