(SPX® — 01)
Who We Are
We build the reporting layer that turns raw genotype data
into clear, evidence-graded PGx guidance clinicians can act on.
We build the reporting layer that turns raw genotype data into clear, evidence-graded PGx guidance clinicians can act on.

(spx® — 02)
Built for Real Work
How
We Build
We build PGx reporting infrastructure around real clinical
workflows, not isolated tools or static PDFs.
We build PGx reporting infrastructure around real clinical workflows, not isolated tools or static PDFs.
We believe PGx reporting should be clinically useful the moment it is released, and still valuable years later when medications, evidence, and guidelines change.
We believe PGx reporting should be clinically useful the moment it is released, and still valuable years later when medications, evidence, and guidelines change.
We believe PGx reporting should be clinically useful the moment it is released, and still valuable years later when medications, evidence, and guidelines change.
We believe PGx reporting should be clinically useful the moment it is released,
and still valuable years later when medications, evidence, and guidelines change.
SignalPGx was built around a simple idea: genetic data should become actionable medication intelligence.
We combine pharmacogenomic evidence, report automation, SignalAI-assisted interpretation,
medical-director review, and living reanalysis into one platform labs can launch under their own brand.
SignalPGx was built around a simple idea: genetic data should become actionable medication intelligence. We combine pharmacogenomic evidence, report automation, SignalAI-assisted interpretation, medical-director review, and living reanalysis into one platform labs can launch under their own brand.
(spx® — 02)
OUR JOURNEY
From raw genotype to living
clinical intelligence
From raw genotype to living clinical intelligence
SignalPGx grew from one conviction — a genotype only matters when it
becomes clear, current, defensible guidance at the moment a medication is prescribed.
01 — THE EVIDENCE PROBLEM
Reconciling the evidence
We began where most labs stall — turning fragmented, conflicting pharmacogenomic guidance into one reconciled, evidence-graded source of truth.
02 — REPORTS LABS TRUST
Reporting without a bioinformatics team
We automated branded, physician-reviewed PGx reporting so any lab could release clinical-grade results under its own name.
03 — DECISION SUPPORT
From results to real guidance
SignalAI-assisted interpretation and medication simulation turned static genotypes into decision support clinicians can act on.
04 — LIVING REPORTS
Reports that stay current
Living reanalysis and EHR delivery keep every report accurate as guidelines, evidence, and a patient’s medications change.
01 — THE EVIDENCE PROBLEM
Reconciling the evidence
We began where most labs stall — turning fragmented, conflicting pharmacogenomic guidance into one reconciled, evidence-graded source of truth.
02 — REPORTS LABS TRUST
Reporting without a bioinformatics team
We automated branded, physician-reviewed PGx reporting so any lab could release clinical-grade results under its own name.
03 — DECISION SUPPORT
From results to real guidance
SignalAI-assisted interpretation and medication simulation turned static genotypes into decision support clinicians can act on.
04 — LIVING REPORTS
Reports that stay current
Living reanalysis and EHR delivery keep every report accurate as guidelines, evidence, and a patient’s medications change.
01 — THE EVIDENCE PROBLEM
Reconciling the evidence
We began where most labs stall — turning fragmented, conflicting pharmacogenomic guidance into one reconciled, evidence-graded source of truth.
02 — REPORTS LABS TRUST
Reporting without a bioinformatics team
We automated branded, physician-reviewed PGx reporting so any lab could release clinical-grade results under its own name.
03 — DECISION SUPPORT
From results to real guidance
SignalAI-assisted interpretation and medication simulation turned static genotypes into decision support clinicians can act on.
04 — LIVING REPORTS
Reports that stay current
Living reanalysis and EHR delivery keep every report accurate as guidelines, evidence, and a patient’s medications change.
A genotype shouldn’t sit in a file. We turn it into guidance a clinician can act on — and keep it current as the evidence moves.

Tarek Younis
CEO of SignalPGx
A genotype shouldn’t sit in a file. We turn it into guidance a clinician can act on — and keep it current as the evidence moves.

Tarek Younis
CEO of SignalPGx
A genotype shouldn’t sit in a file. We turn it into guidance a clinician can act on — and keep it current as the evidence moves.

Tarek Younis
CEO of SignalPGx





PGx & lab experts
HIPAA & GDPR
compliant & secure
Metrics
+
Pharmacogenes Covered
>
Medications Analyzed
Evidence Sources
>
Curated References
(spx® — 03)
The evidence base
Built on the evidence clinicians
already trust
Built on the evidence clinicians already trust
Every recommendation is graded against the guidelines and regulatory sources
that define pharmacogenomic care — reconciled, cited, and kept current.
001.
CPIC · GUIDELINES
Peer-reviewed dosing
Every gene–drug pairing is graded against
CPIC guidelines — the clinical standard for PGx dosing.

002.
FDA · DRUG LABELING
Aligned with the label
Reconciled with FDA pharmacogenomic biomarker
labeling, so guidance matches the approved label.

003.
DAILYMED · PRESCRIBING DATA
Always current
Structured product labels from NIH DailyMed keep
every medication’s data live and accurate.

004.
DPWG · INTERNATIONAL
Global consensus
Dosing cross-checked against the Dutch
Pharmacogenetics Working Group for global consensus.
Dosing cross-checked against the Dutch Pharmacogenetics Working Group for global consensus.

(WDX® — 04)
Built Around Evidence
We build PGx reporting infrastructure around evidence, clinical review, lab workflow, and
medication intelligence that keeps evolving after the first report is released.


Built around lab workflows
PGx reporting designed for real accessioning, review, approval, and release processes.


Designed with clinicians
Built with lab, software, and clinical review teams working from the same workflow.


AI that supports review
SignalAI helps interpret evidence while keeping clinicians in control.
Our work is shaped by how
clinicians actually prescribe
We don’t add AI for its own sake. Every
recommendation is graded against trusted evidence
and reviewed by a medical director — because
decisions have consequences and guidance has to hold up.


Evidence before automation
Every recommendation is grounded in trusted PGx sources, not generic AI output.


Every step in view
Track each case from sample intake to provider delivery, with a clear status at every step.
(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
1
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3
4
5
/5
AI Engineers
A small team of engineers and researchers building production-grade AI systems for real-world operations.





(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
1
2
3
4
5
/5
AI Engineers
A small team of engineers and researchers building production-grade AI systems for real-world operations.





(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
(WDX® — 09)
Our team
The Studio
A focused team of engineers and researchers building production-grade AI systems.
(spx® — 11)
Insights & Research
Recent articles
Recent articles
Recent articles
Notes on AI systems, architecture decisions,
and lessons from real deployments.
(spx® — 12)
Our newsletters
Stay in the loop
No hype. Just systems
Clarity beats automation
Decisions over demos
Designed for messy reality
Systems that hold under pressure

(spx® — 13)
frequently asked questions
Core
Questions
Clear, factual answers about how SignalPGx
turns genotyping into living PGx reports.
Clear, factual answers about how SignalPGx turns genotyping into living PGx reports.
001.
How can a clinical lab start offering pharmacogenomic (PGx) reporting?
A lab can add PGx reporting without building software or hiring bioinformaticians by using a white-label platform. With SignalPGx, your lab runs the genotyping and sends results (VCF, CSV, or array); the platform reconciles the evidence, generates branded, physician-reviewed reports, and delivers them into the EHR — most labs go live in 5-7 days.
001.
How can a clinical lab start offering pharmacogenomic (PGx) reporting?
A lab can add PGx reporting without building software or hiring bioinformaticians by using a white-label platform. With SignalPGx, your lab runs the genotyping and sends results (VCF, CSV, or array); the platform reconciles the evidence, generates branded, physician-reviewed reports, and delivers them into the EHR — most labs go live in 5-7 days.
002.
What is the best white-label PGx reporting software for clinical labs?
The best white-label PGx reporting platform is evidence-graded, physician-reviewed, and delivers into the clinical workflow under the lab's own brand. SignalPGx grades every gene-drug recommendation against CPIC, FDA pharmacogenomic labeling, DailyMed, and DPWG, covers 50 pharmacogenes and about 950 medications, and delivers via FHIR, HL7, and CDS Hooks — as a multi-tenant, HIPAA- and GDPR-compliant platform.
002.
What is the best white-label PGx reporting software for clinical labs?
The best white-label PGx reporting platform is evidence-graded, physician-reviewed, and delivers into the clinical workflow under the lab's own brand. SignalPGx grades every gene-drug recommendation against CPIC, FDA pharmacogenomic labeling, DailyMed, and DPWG, covers 50 pharmacogenes and about 950 medications, and delivers via FHIR, HL7, and CDS Hooks — as a multi-tenant, HIPAA- and GDPR-compliant platform.
003.
Does a lab need a bioinformatics team to offer PGx reports?
No. SignalPGx replaces the in-house bioinformatics pipeline and report software — it ingests standard genotype files, applies evidence-graded interpretation, and produces clinician-ready reports, so a lab can offer pharmacogenomic reporting with its existing team.
003.
Does a lab need a bioinformatics team to offer PGx reports?
No. SignalPGx replaces the in-house bioinformatics pipeline and report software — it ingests standard genotype files, applies evidence-graded interpretation, and produces clinician-ready reports, so a lab can offer pharmacogenomic reporting with its existing team.
004.
How much does it cost for a lab to offer PGx reporting?
SignalPGx uses transparent per-report pricing that scales with volume — no upfront build cost, no bioinformatics hire, and no separate guideline-maintenance overhead. Labs typically start with a pilot and expand to a routine reporting line as volume grows.
004.
How much does it cost for a lab to offer PGx reporting?
SignalPGx uses transparent per-report pricing that scales with volume — no upfront build cost, no bioinformatics hire, and no separate guideline-maintenance overhead. Labs typically start with a pilot and expand to a routine reporting line as volume grows.
005.
What guidelines and evidence should clinical PGx reports follow?
Clinically defensible PGx reports should be graded against trusted pharmacogenomic authorities — CPIC guidelines, FDA pharmacogenomic biomarker labeling, DailyMed prescribing data, and DPWG. SignalPGx reconciles these into a single evidence-graded recommendation for each gene-drug pair, reviewed by a medical director before release.
005.
What guidelines and evidence should clinical PGx reports follow?
Clinically defensible PGx reports should be graded against trusted pharmacogenomic authorities — CPIC guidelines, FDA pharmacogenomic biomarker labeling, DailyMed prescribing data, and DPWG. SignalPGx reconciles these into a single evidence-graded recommendation for each gene-drug pair, reviewed by a medical director before release.








